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At the end of the Edo period, Manji visited Kyoto with Ryoma SAKAMOTO. After the Battle of Ikedaya, the momentum of Joi-ha (supporters of the expulsion of foreigners) was lost. Manji headed for Choshu under the guidance of Nakaoka Shintaro, and cooperated with the coup d'etat of Shinsaku Takasugi, a rare revolutionary, leading to a successful coup d'etat. On the other hand, Ayame 歩蘭, a doctor, entered the basement of Edo-jo Castle. He burned Manji's "original" right hand and tried to escape from the Port of Yokohama. A few months later, the Satsuma-Choshu Alliance was established, and Ryoma, one of the key players in the Alliance, became the target of his life.